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Introduction to Radiens#

One software platform for neural recording and analysis#

Research use only. NeuroNexus products and the procedures described here are for non-clinical research use, and must not be used in human or veterinary medical procedures.

Radiens from NeuroNexus is a single, scalable software platform that spans the electrophysiology workflow — from recording to result. It reads any acquisition stream live, carries a recording through acquisition, curation, analysis, and exploration, and keeps your data on your own hardware.

Audience: Users, lab managers, researchers, purchasing departments, and system administrators evaluating neural recording software

What Radiens is#

Radiens is one integrated platform whose applications cover every stage of electrophysiology research:

• Adapts to your protocols: The platform fits changing experimental protocols and requirements.
• Clear interfaces: Designed for efficient research workflows with a short learning curve.
• Broad compatibility: Works with diverse neuroscience hardware and existing software.
• Scales with the work: From single-cell to large-scale network recordings, from your workstation to on-demand cluster.

Built for research workflows#

• Research-specific design: Built for neuroscience workflows and experimental requirements.
• Flexible architecture: Accommodates diverse research paradigms and evolving protocols.
• Cross-platform: Consistent operation across Windows, macOS, Linux, and Apple silicon.
• Extensible: Python and MATLAB APIs for custom development.

Key capabilities#

Interactive visualization and modeling#

• Interactive probe models: 3D visualization of electrode-array configurations.
• Automated probe mapping: Recognition and mapping of probe geometries.
• Brain- and target-centered models: Atlas integration for anatomical context.
• Real-time visualization: Live display of neural activity during recording.

Spatial analysis#

• 3D neural-activity mapping: Spatial representation of neural data.
• Anatomical registration: Alignment of recording data with atlas coordinates.
• Multi-dimensional analysis: Spatial, temporal, and functional dimensions together.
• Interactive exploration: Adjust visualization parameters for detailed analysis.

Signal processing#

Live and post-hoc analysis#

• Real-time spike sorting: Live isolation and classification of neural units during recording.
• Post-hoc spike sorting: Spike sorting after the session, with version-pinned open-source pipelines (Kilosort, SpikeInterface).
• Signal-quality metrics: Continuous assessment of recording quality and electrode performance.
• Flexible referencing: Quick optimization of recording configurations.

Data processing#

• Filtering: Signal conditioning and noise-reduction algorithms.
• Artifact handling: Identification and removal of recording artifacts.
• Signal enhancement: Improve signal-to-noise ratio.
• Multi-channel processing: High-density electrode arrays (1,024+ channels).

Cross-platform support#

• Windows / macOS / Linux: Full feature support, with native performance on Apple silicon.
• Python API: Programmatic control and custom analysis.
• MATLAB integration: Works with MATLAB analysis workflows.
• Third-party integration: Compatible with existing research software.

The applications#

Allego — real-time acquisition and control#

• Instrument control: Direct control of data-acquisition hardware.
• Real-time analytics: Live analysis and visualization during collection.
• Live monitoring: Continuous assessment of system performance and data quality.
• Probe-centered interface: The interface is organized around probe configurations and workflows.
• Plug-and-play: Automatic recognition of connected hardware with minimal setup.
• Impedance checking and referencing: Electrode validation and reference optimization.

Videre — analysis, curation, and exploration#

Videre is the analysis and exploration surface. Curation and analysis are workflow stages within it, not separate products.

• Analysis and exploration: Work through stored electrophysiology data with spatial and target-centered views.
• Curation: Organize, validate, and annotate datasets; quality and provenance travel with the data.
• File conversion: Convert to .nex, NWB, and .bin with lossless preservation and batch processing.
• Signal conditioning: Configurable digital filtering with real-time preview.
• Data slicing: Extract by time period or channel for targeted analysis.
• Signal-quality metrics: Quantitative assessment and quality reporting.
• Publication-ready graphics: High-resolution 3D visualizations for manuscripts.

RadiensPy — the free Python client#

• Full programmatic control: Everything the applications do, via Python and MATLAB scripts.
• Well-documented API: For scripting and composition.
• Scriptable and agent-operable: A clean, structured interface (JSON, markdown, stdout).
• PyPI availability: Install through the Python Package Index.
• Python ecosystem: Integrates with the broader scientific-computing stack.

Data management with Allego#

The .xdat file format#

• Simple and efficient: A file format designed for electrophysiology data.
• Component structure: Distinct components for binary sample data, timestamps, and metadata.
• JSON metadata: Experimental metadata in a human-readable format.
• Compatible: Works with common electrophysiology analysis software.

Format compatibility#

• NeuroExplorer: Integration with NeuroExplorer analysis workflows.
• Plexon: Compatibility with Plexon data.
• NWB: Full support for the Neurodata Without Borders standard.
• Kilosort: Integration with Kilosort spike-sorting output.

System requirements and compatibility#

Hardware#

• Memory: 16 GB RAM minimum (32 GB recommended for >256 channels).
• Storage: Fast SSD for data throughput.
• Processing: High-performance CPU and GPU for real-time analysis.
• Connectivity: USB 3.0 for high-speed data transfer.
• Platform: Cross-platform across major operating systems.

Acquisition hardware#

Instrument control ships for - Smartbox (and Smartbox Pro). - SiNAPS active-probe systems. - XDAQ — CORE2, ONE+ and ALL-IN-ONE.

Other systems

• Open Ephys: Open Ephys acquisition hardware.
• Intan: Intan RHD USB interface and 512/1,024-channel recording controllers.
• Model builder: Covers non-native electrodes and headstages.

Editions#

Radiens is built for serious science and free to start. The Standard edition is free; Pro backs your work at its scale. Real-time monitoring is delivered through Vantage™ — a live view of the recording, signal quality, and live PSD in the free tier, with live spectral, live sorting, live PSTH, and any-DAQ recording monitoring at Pro. See Choose the Right Radiens Package.

Support#

• Documentation: Reference for all software components.
• Tutorials: Step-by-step guides for common research applications.
• Technical support: Help from NeuroNexus specialists.
• Community: A user community for knowledge sharing.

Summary#

Radiens is one platform for data acquisition, analysis, and visualization — real-time capabilities, post-hoc analysis, spatial visualization, and broad hardware and format compatibility, on a single engine. Its modular applications let you use the surfaces your work needs, and its Python and CLI interfaces make the whole platform scriptable and agent-operable — while your data stays home and every result stays re-derivable.

From recording to result.

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Related documentation#

• Welcome to Radiens
• Choose the Right Radiens Package
• Radiens System Requirements
• X-Series XDAQ System

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For installation guides, configuration options, or training programs, contact NeuroNexus technical support for Radiens software assistance.